Crop Biotech Update

CRISPR Improves Resistance of Soybeans to Soybean Mosaic Virus

August 28, 2024

Experts from Nanjing Agricultural University and partners used CRISPR to develop soybeans with enhanced resistance to soybean mosaic virus (SMV). Their study, published in The Crop Journal, contributes to the ongoing research efforts to manage viral diseases in soybeans.

SMV is a virus causing significant threats to the yield and seed production quality of soybeans. It is the most widespread virus in soybean cropping regions, leading to reduced grain yields by as much as 15% to 35% under natural field conditions. Hence, developing a gene-edited soybean variety became a high priority for improved productivity.

The study used multiple CRISPR-CasRx antiviral systems to confer resistance against SMV. The study revealed that the CRISPR-CasRx(+) strategy exhibited the greatest level of SMV resistance. 39.02% of T1 plants are highly resistant (HR) and 35.77% are resistant (R), while only 6.50% were susceptible (S) to SMV. The results showed that SMV accumulation was significantly decreased or even undetectable in HR and R plants. These findings provide new insights to improve soybean resistant to SMV.

For more information, read the article from The Crop Journal.


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