Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Microparticle bombardment of plant cells or tissue

GM Trait s :
Lepidopteran insect resistance , Antibiotic resistance , Visual marker

Commercial Trait:
(Stacked)  Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
cry1Ac	Bacillus thuringiensis subsp. Kurstaki strain HD73	Cry1Ac delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
nptII  *	Escherichia coli Tn5 transposon	neomycin phosphotransferase II enzyme	allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  *	Escherichia coli	3''(9)-O-aminoglycoside adenylyltransferase enzyme	allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin
uidA  *	Escherichia coli	beta-D-glucuronidase (GUS) enzyme	produces blue stain on treated transformed tissue, which allows visual selection
cry2Ab2	Bacillus thuringiensis subsp. kumamotoensis	Cry2Ab delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Australia
Brazil
Burkina Faso
Canada
China
Colombia
Costa Rica
European Union
India
Japan
Mexico
New Zealand
Nigeria
Philippines
Singapore
South Africa
South Korea
Taiwan
United States

 

Event Description

• CBD Biosafety Clearing House
• CERA GM Crop Database

Regulatory and Biosafety Information

• Agri-Food and Veterinary Authority of Singapore
• Agri-Food and Veterinary Authority of Singapore
• Bureau of Plant Industry - Philippines
• Canadian Food Inspection Agency
• CBD Biosafety Clearing House
• Food Standards Australia New Zealand
• GEAC Biosafety Data of Approved GM crops
• India Biosafety Clearing House Decision
• Japan Biosafety Clearing House
• Office of the Gene Technology Regulator - Australia
• Office of the Gene Technology Regulator - Australia
• Taiwan Food and Drug Administration
• US Department of Agriculture - APHIS
• US Food and Drug Administration
• US Food and Drug Administration
• USDA-FAS GAIN Report - China 2018
• USDA-FAS GAIN Report - India 2018

Detection Methods

• EU Reference Laboratory for GM Food and Feed
• GMO Detection Method Database