Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance , Visual marker , Dicamba herbicide tolerance

Commercial Trait:
(Stacked)  Herbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
dmo	Stenotrophomonas maltophilia strain DI-6	dicamba mono-oxygenase enzyme	confers tolerance to the herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) by using dicamba as substrate in an enzymatic reaction
bar	Streptomyces hygroscopicus	phosphinothricin N-acetyltransferase (PAT) enzyme	eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation
cp4 epsps (aroA:CP4)	Agrobacterium tumefaciens strain CP4	herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme	decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
cry1Ac	Bacillus thuringiensis subsp. Kurstaki strain HD73	Cry1Ac delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
nptII  *	Escherichia coli Tn5 transposon	neomycin phosphotransferase II enzyme	allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  *	Escherichia coli	3''(9)-O-aminoglycoside adenylyltransferase enzyme	allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin
uidA  *	Escherichia coli	beta-D-glucuronidase (GUS) enzyme	produces blue stain on treated transformed tissue, which allows visual selection
cry2Ab2	Bacillus thuringiensis subsp. kumamotoensis	Cry2Ab delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Japan
Mexico
South Korea
Taiwan

 

Regulatory and Biosafety Information

• CIBIOGEM - Mexico
• Japan Biosafety Clearing House
• Japan Biosafety Clearing House
• Korea Biosafety Clearing House
• Taiwan Food and Drug Administration