Developer:
Syngenta and Monsanto Company

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Coleopteran insect resistance , Lepidopteran insect resistance , Antibiotic resistance , Mannose metabolism

Commercial Trait:
(Stacked)  Herbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
cp4 epsps (aroA:CP4)	Agrobacterium tumefaciens strain CP4	herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme	decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
cry1Ab	Bacillus thuringiensis subsp. kurstaki	Cry1Ab delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry1F	Bacillus thuringiensis var. aizawai	Cry1F delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry34Ab1	Bacillus thuringiensis strain PS149B1	Cry34Ab1 delta-endotoxin	confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining
cry35Ab1	Bacillus thuringiensis strain PS149B1	Cry35Ab1 delta-endotoxin	confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining
pat	Streptomyces viridochromogenes	phosphinothricin N-acetyltransferase (PAT) enzyme	eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation
goxv247  *	Ochrobactrum anthropi strain LBAA	glyphosate oxidase	confers tolerance to glyphosate herbicides by degrading glyphosate into aminomethylphosphonic acid (AMPA) and glyoxylate
nptII  *	Escherichia coli Tn5 transposon	neomycin phosphotransferase II enzyme	allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
pmi  *	Escherichia coli	Phosphomannose Isomerase (PMI) enzyme	metabolizes mannose and allows positive selection for recovery of transformed plants

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Canada
Colombia
Japan
Mexico
South Korea
Taiwan

 

Regulatory and Biosafety Information

• Canadian Food Inspection Agency
• FAO GM Foods Platform (Mexico)
• INVIMA - Colombia
• Korean Biosafety Clearing House
• Taiwan Food and Drug Administration