Event Name: MIR604
Event Code : SYN-IR6Ø4-5
Trade Name: Agrisure™ RW
Crop: Zea mays L. - Maize, Corn
Developer: Syngenta
Method of Trait Introduction: Agrobacterium tumefaciens-mediated plant transformation
GM Traits: Coleopteran insect resistance , Mannose metabolism
Commercial Trait: (Singular) Insect Resistance
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| mcry3A | synthetic form of cry3A gene from Bacillus thuringiensis subsp. tenebrionis | modified Cry3A delta-endotoxin | confers resistance to coleopteran insects particularly corn rootworm pests by selectively damaging their midgut lining |
| pmi * | Escherichia coli | Phosphomannose Isomerase (PMI) enzyme | metabolizes mannose and allows positive selection for recovery of transformed plants |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Argentina | |||
| Australia | |||
| Brazil | |||
| Canada | |||
| China | |||
| Colombia | |||
| European Union | |||
| Indonesia | |||
| Japan | |||
| Malaysia | |||
| Mexico | |||
| New Zealand | |||
| Philippines | |||
| Russia | |||
| Singapore | |||
| South Africa | |||
| South Korea | |||
| Taiwan | |||
| Thailand | |||
| Turkey | |||
| United States | |||
| Vietnam |
* point mouse arrow over year for notes
Last updated: July 22, 2022
Documents and Links
Event Description
Regulatory and Biosafety Information
- Agri-Food and Veterinary Authority of Singapore
- Canadian Food Inspection Agency
- CBD Biosafety Clearing House
- CIB - Brazil
- European Food Safety Authority
- Food Standards Australia New Zealand
- Japan Biosafety Clearing House
- Malaysia Biosafety Clearing House
- Ministry of Agriculture and Rural Government - Vietnam
- Status of Application for Direct Use-Philippines
- Turkish Biosafety Board Decision
- US Department of Agriculture - APHIS
- US Environmental Protection Agency
- US Food and Drug Administration
- USDA-FAS GAIN Report - China 2018
Detection Methods
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.