CRISPR-Based Editing of Wheat to Reduce ImmunoreactivityNovember 29, 2023
Researchers used CRISPR to edit gluten-encoding genes of wheat to reduce immunoreactivity. The modification did not affect the quality of the grain protein.
Wheat immunotoxicity is linked to an aberrant response to gluten-derived peptides. Breeding and biotechnology were utilized to minimize immunotoxicity, but they affected the dough quality. That's why the researchers decided to try using CRISPR-Cas9 to address this issue.
The team mutated or deleted the ω- and γ-gliadin gene copies that were abundant in immunoreactive peptides. The findings show that the decrease in ω- and γ-gliadin content did not have an adverse effect on the quality characteristics of dough and grain protein.
For more information, read the journal article on Plant Biotechnology Journal.
You might also like:
- Pocket K No. 38: Biotech Wheat
- Pocket K No. 60: Rust-resistant Wheat
- Egyptian Researchers Develop GM Wheat with Resistance to Salinity and Water Scarcity
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
- Research Reveals Quinoa's Bladder Cells Protect Against Pests and Diseases; Key to 'Super Quinoa'
- Nigeria's GM Potato Project First-year Trial Shows 300% Yield Advantage
- Experts Discuss the Role of Biotechnology in Sustainable Agriculture
- Experts Reveal Success of CRISPR in Improving Fish
- Gene Editing Reduces Anxiety and Increases Food Intake in Japanese Medaka
- ISAAA and BFAR7 Share Benefits of Stock Enhancement of Blue Swimming Crab
- Six Decades of Ensuring Food Safety with Codex Alimentarius
- New Algorithm Discovers 188 CRISPR Gene Editing Systems
Read the latest:
- Biotech Updates (February 28, 2024)
- Gene Editing Supplement (February 28, 2024)
- Gene Drive Supplement (February 22, 2023)
Subscribe to BU: