MON88913 x MON15985 | GM Approval Database- ISAAA.org

Event Name: MON88913 x MON15985

Event Code : MON-88913-8 x MON-15985-7
Trade Name: Roundup Ready™ Flex™ Bollgard II™ Cotton

Crop: Gossypium hirsutum L. - Cotton

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Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance , Visual marker

Commercial Trait:
(StackedHerbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function
cp4 epsps (aroA:CP4) Agrobacterium tumefaciens strain CP4 herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
cry2Ab2 Bacillus thuringiensis subsp. kumamotoensis Cry2Ab delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry1Ac Bacillus thuringiensis subsp. Kurstaki strain HD73 Cry1Ac delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
uidA  * Escherichia coli beta-D-glucuronidase¬†(GUS) enzyme produces blue stain on treated transformed tissue, which allows visual selection
nptII  * Escherichia coli Tn5 transposon neomycin phosphotransferase II enzyme allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  * Escherichia coli 3''(9)-O-aminoglycoside adenylyltransferase enzyme allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin


 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country Food
direct use or processing
Feed
direct use or processing
Cultivation
domestic or non-domestic use
Australia      
Brazil      
Colombia      
Costa Rica      
Japan      
Mexico      
New Zealand      
Paraguay      
Philippines      
South Africa      
South Korea      
Taiwan      
This event in G. barbadense was approved in 2008.
This event in G. barbadense was approved in 2008.
renewal 2011 renewal 2018
renewal 2011 renewal 2018

 * point mouse arrow over year for notes

Last updated: September 9, 2018