COT102 x MON15985 x MON88913 x MON88701 | GM Approval Database- ISAAA.org

Event Name: COT102 x MON15985 x MON88913 x MON88701

Event Code : SYN-IR1Ø2-7 x MON-15985-7 x MON-88913-8 x MON 887Ø1-3
Trade Name: n/a

Crop: Gossypium hirsutum L. - Cotton

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Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance , Visual marker , Dicamba herbicide tolerance

Commercial Trait:
(StackedHerbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function
cp4 epsps (aroA:CP4) Agrobacterium tumefaciens strain CP4 herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
vip3A(a) Bacillus thuringiensis strain AB88 VIP3A vegetative insecticidal protein confers resistance to feeding damage caused by lepidopteran insects by selectively damaging their midgut lining
aph4 (hpt)  * Escherichia coli hygromycin-B phosphotransferase (hph) enzyme allows selection for resistance to the antibiotic hygromycin B
cry1Ac Bacillus thuringiensis subsp. Kurstaki strain HD73 Cry1Ac delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry2Ab2 Bacillus thuringiensis subsp. kumamotoensis Cry2Ab delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
nptII  * Escherichia coli Tn5 transposon neomycin phosphotransferase II enzyme allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  * Escherichia coli 3''(9)-O-aminoglycoside adenylyltransferase enzyme allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin
uidA  * Escherichia coli beta-D-glucuronidase (GUS) enzyme produces blue stain on treated transformed tissue, which allows visual selection
dmo Stenotrophomonas maltophilia strain DI-6 dicamba mono-oxygenase enzyme confers tolerance to the herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) by using dicamba as substrate in an enzymatic reaction
bar Streptomyces hygroscopicus phosphinothricin N-acetyltransferase (PAT) enzyme eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation


 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country Food
direct use or processing
Feed
direct use or processing
Cultivation
domestic or non-domestic use
Australia      
Brazil      
Colombia      
Japan      
Mexico      
South Korea      
Taiwan      
Type 1 cultivation

 * point mouse arrow over year for notes

Last updated: December 4, 2018