NK603 x MON810 x 4114 x MIR604 | GM Approval Database- ISAAA.org

Event Name: NK603 x MON810 x 4114 x MIR604

Event Code : MON-00603-6 x MON-00810-6 x DP004114-3 x SYN-IR604-4
Trade Name: Not available

Crop: Zea mays L. - Maize, Corn

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Developer:
Syngenta and Monsanto Company

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Coleopteran insect resistance , Lepidopteran insect resistance , Antibiotic resistance , Mannose metabolism

Commercial Trait:
(StackedHerbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function
cp4 epsps (aroA:CP4) Agrobacterium tumefaciens strain CP4 herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
cry1Ab Bacillus thuringiensis subsp. kurstaki Cry1Ab delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry1F Bacillus thuringiensis var. aizawai Cry1F delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry34Ab1 Bacillus thuringiensis strain PS149B1 Cry34Ab1 delta-endotoxin confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining
cry35Ab1 Bacillus thuringiensis strain PS149B1 Cry35Ab1 delta-endotoxin confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining
pat Streptomyces viridochromogenes phosphinothricin N-acetyltransferase (PAT) enzyme eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation
goxv247  * Ochrobactrum anthropi┬ástrain LBAA glyphosate oxidase confers tolerance to glyphosate herbicides by degrading glyphosate into aminomethylphosphonic acid (AMPA) and glyoxylate
nptII  * Escherichia coli Tn5 transposon neomycin phosphotransferase II enzyme allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
pmi  * Escherichia coli Phosphomannose Isomerase (PMI) enzyme metabolizes mannose and allows positive selection for recovery of transformed plants


 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country Food
direct use or processing
Feed
direct use or processing
Cultivation
domestic or non-domestic use
Canada      
Colombia      
Japan      
Mexico      
South Korea      
Taiwan      
Type 1 Cultivation, including all intermediates that can be derived from the individual lines not previously granted Type 1 Use

 * point mouse arrow over year for notes

Last updated: August 19, 2018